Scientific Programme
Programme Changes in red colour
Plenary Lectures
Sunday, September 7, 2008 18:30 – 19:30
The potential and the challenges in applying thermodynamics to whole-cell biochemical engineering
U. von Stockar, EPFL/CH
Monday, September 8, 2008 9:00 – 9:45
The sugar industry: the cradle of biochemical engineering
J. Villadsen, Technical University of Denmark, Lyngby/DK
Monday, September 8, 2008 14:00 – 14:45
High-throughput molecular bioprocessing: a new addition to biochemical engineering science
J.S. Dordick, Rensselaer Polytechnic Institute, Troy, NY/USA
Monday, September 8, 2008 16:55 – 17:40
A perspective of the development of the field metabolic engineering from the early days of J. Bailey until today
V. Hatzimanikatis, EPFL/CH
Tuesday, September 9, 2008 9:00 – 9:45
Biopharmaceutical process development – a regulatory perspective on the future
A. Staby
, Novo Nordisk A/S, Bagsværd/DK
Wednesday, September 10, 2008 9:00 – 9:45
Sustainable production of bio fuels and bio commodity products – chances and challenges
M. Narodoslawsky, Technical University of Graz/A
Lecture Programme
Sunday, September 7, 2008
13:00 Registration for workshop participants
14:00 - 17:00 Workshop 1: Analysis of Genomic Data with R and Bioconductor (Th. Scharl)
14:00 - 17:00 Workshop 2: Molecular Dynamics Simulations of Proteins (P. Martel)
14:00 - 17:00 Workshop 3: Quality by Design (C.-F. Mandenius)
Description of each workshop
15:00 Registration for conference participants
Room: University Auditorium, building 4
18:00
Opening
Chair: A. Jungbauer, University of Natural Resources and Applied Life Sciences, Vienna/A
18:30
Evening Lecture:
The potential and the challenges in applying thermodynamics to whole-cell biochemical engineering
U. von Stockar, EPFL/CH
19:30 - 21:00 Welcome Reception
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Monday, September 8, 2008
Room: University Auditorium, building 4
Chair: M. Berovic, University of Ljubljana/SLO
09:00
Plenary Lecture: The sugar industry: the cradle of biochemical engineering
J. Villadsen, Technical University of Denmark, Lyngby/DK
09:45 Coffee Break
Room: Auditorium 1.16, building 8/9
Bioreaction Engineering
Chair: J. Villadsen, Technical University of Denmark, Lyngby/DK
10:05
Engineering challenges in the production of baculovirus vectors for gene therapy
V. Bernal
, N. Carinhas, A.Y. Yokomizo, T. Vicente, Universidade Nova de Lisboa, Oeiras/P; R. Oliveira, M.J.T. Carrondo, Universidade Nova de Lisboa, Oeiras and Universidade Nova de Lisboa, Caparica/P; P.M. Alves, Universidade Nova de Lisboa, Oeiras/P
10:30
MPEC - microparticle-enhanced cultivation: a novel method for submerged cultivation of filamentous microorganisms
M. Pescheck, K. Ehrich, B. Kaup, J. Schrader ,
M. Buchhaupt
, DECHEMA e.V., Frankfurt am Main/D
10:55
Flow cytometric analysis of recombinant antibody fragment production in Escherichia coli under batch and fed-batch cultures
A.J. Want
, University of Birmingham/UK; J. Liddell, B. Kara, Avecia Biologics Ltd., Billingham/UK; O.R.T. Thomas, University of Birmingham/UK; C.J. Hewitt, Loughborough University/UK
(
now at 16:00
: Production of bioplastics (PHA) from sugar cane molasses
M.G.E. Albuquerque
, C. Torres, Universidade Nova de Lisboa/P; S. Bengtsson, A. Werker, Anoxkaldnes AB, Lund/S; M.A.M. Reis, Universidade Nova de Lisboa/P)
11:20 A novel two stage production process for the lantibiotic gallidermin
G. Medaglia
, G. Valsesia, S. Panke, ETH Zürich/CH
11:45-13:00
General Assembly
of the EFB Section on Biochemical Engineering Science (Room: Auditorium 1.2 - building 8/9)
11:45 Lunch
Room: University Auditorium, building 4
Chair: J. Cabral, Technical University of Lisbon/P
14:00
Plenary Lecture: High-throughput molecular bioprocessing: a new addition to biochemical engineering science
J.S. Dordick, Rensselaer Polytechnic Institute, Troy, NY/USA
14:45 Time for room change
Room: Auditorium 1.16, building 8/9
Bioreaction Engineering
Chair: A. Lübbert, University of Halle-Wittenberg/D
14:50
Physiological, morphological and kinetic aspects of lovastatin biosynthesis by Aspergillus terreus
M. Bizukojc
, S. Ledakowicz, Technical University of Lodz/PL
15:15
Conceptual process design of integrated fermentation, deacylation and crystallization for production of β-lactam antibiotics
C.A. Roa Engel
, A.J.J. Straathof, W.M. van Gulik, Technical University of Delft/NL; E.J.A.X. van de Sandt, T. van der Does, DSM Anti-infectives, Delft/NL; L.A.M. van der Wielen, Technical University of Delft/NL
15:40 Coffee Break
16:00
Production of bioplastics (PHA) from sugar cane molasses
M.G.E. Albuquerque
, C. Torres, Universidade Nova de Lisboa/P; S. Bengtsson, A. Werker, Anoxkaldnes AB, Lund/S; M.A.M. Reis, Universidade Nova de Lisboa/P
(
now at 10:55
: Flow cytometric analysis of recombinant antibody fragment production in Escherichia coli under batch and fed-batch cultures
A.J. Want
, University of Birmingham/UK; J. Liddell, B. Kara, Avecia Biologics Ltd., Billingham/UK; O.R.T. Thomas, University of Birmingham/UK; C.J. Hewitt, Loughborough University/UK)
16:25
The effect of cryopreservation on α-amylase production during 5L batch Bacillus licheniformis fermentations
N.H. Hancocks
, C. Thomas, University of Birmingham/UK; S.M. Stocks, Novozymes Fermentation Pilot Plant, Bagsvaerd/DK; C.J. Hewitt, Loughborough University, Leicestershire/UK
16:50 Time for room change
Room: University Auditorium, building 4
Chair: M. Canovas, University of Murcia/E
16:55
Plenary Lecture: A perspective of the development of the field metabolic engineering from the early days of J. Bailey until today
V. Hatzimanikatis, EPFL/CH
17:40 – 20:00 Poster Party
Room: Auditorium (anfiteatro) 1.8.1, building 8/9
Biocatalysis and Biotransformation
Chair: J. Woodley, Technical University of Denmark, Lyngby/DK
10:05
Multi-level engineering approach to improve ketone reduction by baker’s yeast
R. Kratzer
, S. Egger, B. Nidetzky, Graz University of Technology/A
10:30
Bubble-free oxygenation for enzymatic oxidation of lactose to lactobionic acid
W. Van Hecke
, Universiteit Gent/B; R. Ludwig, University of Natural Resources and Applied Life Sciences Vienna/A; J. Dewulf, Universiteit Gent/B; M. Auly, University of Natural Resources and Applied Life Sciences Vienna/A; T. Messiaen, Universiteit Gent/B; D. Haltrich, University of Natural Resources and Applied Life Sciences Vienna/A; H. Van Langenhove, Universiteit Gent/B
10:55
Cephalexin synthesis by Penicillin G Acylase immobilized in sol-gel
S.M.S.A. Bernardino
, P. Fernandes, L.P. Fonseca, Instituto Superior Técnico, Lisboa/P
11:20
Enzymatic synthesis of fatty acid alkyl esters in miniemulsion
D.P.C. de Barros
, L.P. Fonseca, J.M.S. Cabral, Instituto Superior Técnico, Lisbon/P; C.K. Weiss, K. Landfester, University of Ulm/D
Room: Auditorium (anfiteatro) 1.8.1, building 8/9
Biocatalysis and Biotransformation
Chair: J. Woodley, Technical University of Denmark, Lyngby/DK
14:50
Systems biotechnology for selective whole-cell redox biocatalysis
B. Bühler, D. Kuhn, Technical University of Dortmund/D; J.-B. Park, Ewha Womans University, Seoul/ROK; L.M. Blank,
A. Schmid
, Technical University of Dortmund and ISAS-Institute for Analytical Sciences, Dortmund/D
15:15
Enzymatic gas/solid reactions: an engineering approach
K. Dimoula
, J. Büchs, A.C. Spiess, RWTH Aachen University/D
15:40 Coffee Break
Chair: A. Schmid, Technical University of Dortmund/D
16:00
Penicillin acylase-catalyzed ampicillin synthesis: effect of pH and type of carriers on selectivity and yields
G.F. Silva, Tecnologias Bioenergéticas, Fortaleza/BR; A.K.P.B. Siqueira,
A.L.O. Ferreira
, Universidade Federal do Ceará, Fortaleza/BR
16:25
Membrane and surface properties of Rhodococcus erythropolis cells in two-phase systems
C.C.C.R. de Carvalho, Instituto Superior Técnico, Lisboa/P
16:50 Time for room change
Room: Auditorium 1.2, building 8/9
Bioseparation
Chair: O.R.T. Thomas, University of Birmingham/UK
10:05
Systematic design of downstream processes - generation of process alternatives
K. Bauer
, G. Schembecker, Technical University of Dortmund/D
10:30
Development of chromatography process design database from crude mixture of proteins
T. Ahamed, B.K. Nfor, L.A.M. van der Wielen, P.D.E.M. Verhaert, G.W.K. van Dedem,
M. Ottens
, Delft University of Technology/NL; M.H.M. Eppink, N.V. Organon, Oss/NL; E.J.A.X. van de Sandt, DSM Anti-Infectives, Delft/NL
10:55
Characterization of pore structure of Sartobind Q membrane adsorbent in different buffers and salt concentrations
I. Tatarova,
M. Polakovic
, Slovak University of Technology, Bratislava/SK; R. Faber, Sartorius Stedim Biotech, Göttingen/D
11:20
Innovation in bioseparation with magnetic beads
B. Hickstein
, Clausthal University of Technology/D; T. Käppler, C. Posten, University of Karlsruhe (TH)/D; U.A. Peuker, Clausthal University of Technology/D
11:45 General Assembly of the EFB Section on Biochemical Engineering Science (Room: Auditorium 1.2, building 8/9)
11:45 Lunch
Room: Auditorium 1.2, building 8/9
Bioseparation
Chair: M. Ottens, Delft University of Technology/NL
14:50
Smart little adsorbents!
O.R.T. Thomas, University of Birmingham/UK
15:15
Constant shear affinity filtration: an integrated technology for direct product capture from mammalian cell cultures
P. Francis
, F. Taghipour, C.A. Haynes, University of British Columbia, Vancouver/CDN
15:40 Coffee Break
16:00
Affinity-enhanced partitioning of human antibodies in aqueous two-phase systems
A.M. Azevedo
, P.A.J. Rosa, I.F. Ferreira, Instituto Superior Técnico, Lisboa/P; J. de Vries, R. Korporaal, H.J. Verhoef, T.J. Tisser, Syncom BV, Groningen/NL; M.R. Aires-Barros, Instituto Superior Técnico, Lisboa/P
16:25
Plasmid DNA purification by phenyl boronate affinity chromatography
A.G. Gomes
, A.M. Azevedo, M.R. Aires-Barros, D.M.F. Prazeres, Instituto Superior Técnico, Lisboa/P
16:50 Time for room change
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Tuesday, September 9, 2008
Room: University Auditorium, building 4
Chair: A. Jungbauer, University of Natural Resources and Applied Life Sciences, Vienna/A
09:00
Plenary Lecture: Biopharmaceutical process development - a regulatory perspective on the future
A. Staby
, Novo Nordisk A/S, Bagsværd/DK
09:45 Time for room change
Room: Auditorium (anfiteatro) 1.22, building 8/9
M3C – Modelling, Monitoring, Measurement & Control
Chair: C. Posten, University of Karlsruhe/D
09:50
On-line analysis, modeling and simulation of recombinant protein expression processes with Pichia pastoris
R. Luttmann
, A. Kazemi, S. Treder, E. Werner, M. Eicke, B. Hahn, G. Cornelissen, Hamburg University of Applied Sciences/D
10:15
Mechanistic models for evaluation of alternative fermentation control strategies within a PAT framework
K.V. Gernaey
, E. Albo, J. Woodley, G. Sin, Technical University of Denmark, Lyngby/DK
10:40 Coffee Break
11:00
Interactive visualization of gene clusters to improve the monitoring of E. coli recombinant systems
T. Scharl
, G. Striedner, F. Pötschacher, K. Bayer, University of Natural Resources and Applied Life Sciences, Vienna/A; F. Leisch, University of Munich/D
11:25
Contribution of FT-IR spectroscopy and chemometrics to clinical microbiology - epidemiological typing of Klebsiella pneumoniae
O. Preisner
, Technical University of Lisbon/P; R. Guiomar, J. Machado, National Health Institute Ricardo Jorge, Lisbon/P; J.A. Lopes, University of Porto/P; J.C. Menezes, Technical University of Lisbon/P
11:50
Applying spectroscopic methods and chemometrics to get a snap-shot of physiology in fermentation processes
A. Eliasson Lantz
, P. Ödman, N. Petersen, L. Olsson, K.V. Gernaey, Technical University of Denmark, Lyngby/DK
12:15 Lunch
Room: University Auditorium, building 4
14:00 Poster Award Presentations of Nominated Posters (6 à 5-7 min.)
15:00 Time for room change
Room: Auditorium (anfiteatro) 1.22, building 8/9
Bioreaction Engineering
Chair: B. Nidetzky, Technical University of Graz/A
15:05
Batch and fed-batch production of recombinant human cytochrome P450 3A4
L.F.M. Rosa
, G.N.M. Ferreira, University of Algarve, Faro/P
15:30
Transcriptome analysis of antibody producing NS0 cells in chemostat and perfusion cultures
B. Krampe
, M. Al-Rubeai, University College Dublin/IRL
15:55 Coffee Break
Chair: C.-F. Mandenius, Linköping University/S
16:10
Rational optimisation of Pichia pastoris fed batch cultivation for improved productivity of heterologous proteins
M. Maurer
, University of Natural Resources and Applied Life Sciences Vienna/A; K. Baumann, Universitat Autònoma de Barcelona/E; M. Kühleitner, University of Natural Resources and Applied Life Sciences Vienna/A; P. Ferrer, Universitat Autònoma de Barcelona/E; D. Mattanovich, University of Natural Resources and Applied Life Sciences Vienna/A
16:35
A comparison of traditional Rushton disc turbines with high solidity ratio, up-pumping, axial hydrofoil impellers in 550 L pilot scale aerobic submerged fermentations
S.M. Stocks
, Novozymes A/S, Bagsværd/DK; M.O. Albaek, Technical University of Denmark, Lyngby/DK; A.W. Nienow, The University of Birmingham/UK
17:00 End of Lectures
18:30 Bus Departure from Hotels
19:00-24:00 Dinner and Poster Award
Room: Auditorium 1.16, building 8/9
Engineering Challenges for Biotechnology Industry
Chair: A. Staby, Novo Nordisk A/S, Gentofte/DK
09:50
Process Analytical Technologies (PAT) and process systems engineering
J. Morris
, Newcastle University/UK; Z.-P. Chen, Strathclyde University, Glasgow/UK; D. Lovett, Perceptive Engineering, Daresbury/UK
10:15
Characterization of flow conditions in wave bioreactors using CFDA
A. Öncül
, D. Thévenin, University of Magdeburg/D; Y. Genzel, U. Reichl, MPI for Dynamics of Complex Technical Systems, Magdeburg/D
10:40 Coffee Break
11:00
Baffled microtiter plates - sufficient oxygen for microorganisms
M. Funke
, J. Büchs, RWTH Aachen University/D; F. Kensy, C. Müller, m2p-labs GmbH, Aachen/D
11:25
A test facility for sparger of production-scale-bioreactors
C. Sieblist
, S. Günther, M. Aehle, University Halle-Wittenberg/D; M. Pohlscheidt, M. Jenzsch, Roche Diagnostics GmbH, Penzberg/D; A. Lübbert, University Halle-Wittenberg/D
11:50
Multi-stage-enhanced recovery of human antibodies by aqueous-two phase extraction
P.A.J. Rosa
, A.M. Azevedo, I.F. Ferreira, Instituto Superior Técnico, Lisboa/P; S. Sommerfeld, Bayer Technology Services GmbH, Leverkusen/D; M.R. Aires-Barros, Instituto Superior Técnico, Lisboa/P; W. Baecker, Bayer Technology Services GmbH, Leverkusen/D
12:15 Lunch
Room: Auditorium 1.16, building 8/9
Engineering Challenges for Biotechnology Industry
Chair: K. Graumann, Sandoz GmbH, Kundl/A
15:05
Novel approaches in cell line and process development
K. Sautter
, B. Enenkel, T. Schulz, L. Florin, E. Becker, J. Schaub, C. Clemens, J. Fieder, H. Kaufmann, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss/D
15:30
Experimental and computational tools for in-depth profiling of a recombinant high productivity CHO fed batch cell culture process
J. Schaub
, C. Clemens, W. Rust, M. Lenter, T. Hildebrandt, K. Quast, D. Mennerich, T.W. Schulz, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss/D
15:55 Coffee Break
Chair: T. Schulz, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss/D
16:10
How reproducible can we cultivate microorganisms during recombinant protein production processes
S. Gnoth, A. Kuprijanov, University of Halle-Wittenberg, Halle/Saale/D; R. Simutis, Kaunas University of Technology/LT;
A. Lübbert
, University of Halle-Wittenberg, Halle/Saale/D
16:35
Optimization of inclusion body-based production of single-chain Fv fragments (scFv)
M.K. Eiberle
, H. Hohenblum, M. Graf, Boehringer Ingelheim Austria GmbH, Vienna/A; A. Jungbauer, University of Natural Resources and Applied Life Sciences, Vienna/A; M. Berkemeyer, Boehringer Ingelheim Austria GmbH, Vienna/A
17:00 End of Lectures
Room: Auditorium 1.2, building 8/9
Bioseparation
Chair: S. Hober, Royal Institute of Technology, Stockholm/S
09:50
Plasmid DNA recovery by adsorption on nonporous beads
T. Tarmann
, D. Horner, University of Natural Resources and Applied Life Sciences, Vienna/A; R. Ganja, Boehringer-Ingelheim Austria GmbH, Vienna/A; A. Jungbauer, University of Natural Resources and Applied Life Sciences, Vienna/A
10:15
Capturing of cell culture derived Vaccinia Virus by heparin-affinity chromatography
M.W. Wolff,
MPI for Dynamics of Complex Technical Systems, Magdeburg/D; C. Venzke, University of Magdeburg/D; S. Lehmann, MPI for Dynamics of Complex Technical Systems, Magdeburg/D; S. Post Hansen, R. Djurup, Bavarian Nordic A/S, Kvistgard/DK; R. Faber, Sartorius AG, Göttingen/D; U. Reichl, MPI for Dynamics of Complex Technical Systems and University of Magdeburg/D
10:40 Coffee Break
11:00
On-column refolding of proteins using NPro fusion technology
R. Hahn
, E. Schmöger, B. Kanatschnig, N. Wernig, A. Dürauer, A. Jungbauer, University of Natural Resources and Applied Life Sciences Vienna/A
11:25
Effects of mobile phase modulators on retention and separation of proteins in electrostatic interaction chromatography
M. Abe, P. Akbarzadehlaleh, Y. Sakaguchi, N. Yoshimoto,
S. Yamamoto
, Yamaguchi University, Ube/J
11:50
Potato protein isolation by expanded bed adsorption and ultrafiltration
S. Løkra,
K.O. Strætkvern
, Hedmark University College, Hamar/N
12:15 Lunch
Room: Auditorium 1.2, building 8/9
Biomedical and Tissue Engineering
Chair: J. Cabral, Technical University of Lisbon/P
15:05
Production of a full thickness skin-substitute using an alginate hydrogel scaffold
N. Hunt
, R. Shelton, D. Hukins, L. Grover, University of Birmingham/UK
15:30
Vif as target for the control of HIV-1 infection: use of recombinant VLPs for non-viral molecular therapy
S.S. Soares
, L. Pedro, G.N.M. Ferreira, University of Algarve, Faro/P
15:55 Coffee Break
16:10
A high-throughput 3D cell microarray to study stem cell fate
T.G. Fernandes
, Instituto Superior Técnico, Lisbon/P and Rensselaer Polytechnic Institute, Troy, NY/USA; S.-J. Kown, Rensselaer Polytechnic Institute, Troy, NY/USA; M.-Y. Lee, Solidus Biosciences, Troy, NY/USA; M.M. Diogo, C. Lobato da Silva, Instituto Superior Técnico, Lisbon/P; D.S. Clark, University of California, Berkeley, CA/USA; J.M.S. Cabral, Instituto Superior Técnico, Lisbon/P; J.S. Dordick, Rensselaer Polytechnic Institute, Troy, NY/USA
16:35
New insights in cell cultivation - online oxygen and pH monitoring in multidishes
G.T. John, PreSens Precision Sensing GmbH, Regensburg/D
17:00 End of Lectures
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Wednesday, September 10, 2008
Room: University Auditorium, building 4
Chair: K. Bayer, University of Natural Resources and Applied Life Sciences, Vienna/A
09:00
Plenary Lecture: Sustainable production of bio fuels and bio commodity products - chances and challenges
M. Narodoslawsky, Technical University of Graz/A
09:45 Time for room change
Room: Auditorium (anfiteatro) 1.8.1, building 8/9
Solid State Bioprocession
Chairs: D.A. Mitchell, Universidade Federal do Paraná, Curitiba/BR and M. Berovic, University of Ljubljana/SLO
09:50
Biochemical engineering challenges for solid-state bioprocessing
D.A. Mitchell
, L.F.L. Luz Jr., N. Krieger, Universidade Federal do Paraná, Curitiba/BR
10:15
Production of antitumor extra and intracellular fungal polysaccharides of Grifola frondosa by submerged and solid state cultivation
M. Berovič
, B. Boh, B. Wraber, University of Ljubljana/SLO
10:40 Coffee Break
Chair: M. Berovic, University of Ljubljana/SLO
11:00
The potential of solid-state bioprocessing for the production of rhamnolipid biosurfactants
N. Krieger
, D. Camilios Neto, D.A. Mitchell, Federal University of Paraná, Curitiba/BR
11:25
Lipase production and Penicillium simplicissimum morphology in solid-state and submerged fermentations
M.L.E. Gutarra
, I.A. Guedes, M.G. Godoy, J.N. Silva, U. Lins, L.R. Castilho, D.M.G. Freire, Universidade Federal do Rio de Janeiro/BR
11:50
Integrated bioprocess for the production of the natural antimicrobial monoterpene R-(+)-perillic acid with P. putida
M.-A. Mirata
, J. Schrader, DECHEMA e.V., Frankfurt am Main/D
12:15 Lunch
Room: University Auditorium, building 4
Chair: M. Berovic, University of Ljubljana/SLO
13:15 Malcolm Lilly Award Presentations
14:30 Coffee Break
Room: Auditorium (anfiteatro) 1.8.1, building 8/9
Bioreaction Engineering
Chair: K. Bayer, University of Natural Resources and Applied Life Sciences, Vienna/A
15:00
Development of plant cell-based bioprocesses for cyclotides production
H. Dörnenburg, University of Erlangen-Nuremberg/D
15:25
Metabolic modelling and characterization of uninfected and infected Sf9 cultures – a basis for improving baculovirus vectors production
N. Carinhas
, V. Bernal, A.Y. Yokomizo, T. Vicente, Universidade Nova de Lisboa, Oeiras/P; M.J.T. Carrondo, R. Oliveira, Universidade Nova de Lisboa, Oeiras and Universidade Nova de Lisboa, Caparica/P; P.M. Alves, Universidade Nova de Lisboa, Oeiras/P
15:50
Production of protein nanoparticles in animal cell cultures
L. Pedro
, S.S. Soares, G.N.M. Ferreira, University of Algarve, Faro/P
16:15
Rhamnolipid biosurfactants network: looking for new ways of biosurfactant production based on renewable resources
V. Walter
, F. Leitermann, R. Hausmann, C. Syldatk, University of Karlsruhe/D
16:40 Time for room change
Room: University Auditorium, building 4
16:45-17:10 Malcolm Lilly Award / Closing
Room: Auditorium 1.16, building 8/9
Biofuel Engineering and Sustainability
Chair: M. Narodoslawsky, Technical University of Graz/A
09:50 Technological challenges in biofuel development: efficient fermentation solutions
C. Knocke
, K. Rix, J. Vogt, DASGIP AG, Jülich/D
10:15
Enhanced xylose fermentation by altering the coenzyme preference of xylose reductase in metabolically engineered S. cerevisiae
B. Petschacher,
S. Krahulec
, M. Klimacek, B. Nidetzky, Graz University of Technology/A
10:40 Coffee Break
11:00
Influence of substrate particle size and wet oxidation on physical surface structures and enzymatic hydrolysis of wheat straw
M. Pedersen
, Technical University of Denmark, Lyngby/DK; A. Viksø-Nielsen, Novozymes A/S, Bagsværd/DK; A.S. Meyer, Technical University of Denmark, Lyngby/DK
11:25
High cell density production of polyhydroxyalkanoates from waste glycerol
J. Cavalheiro
, Instituto Superior Técnico, Lisboa/P; C. Almeida, Instituto Superior Técnico, Lisboa and Instituto Superior de Ciências da Saúde Egas Moniz, Monte da Caparica/P; M.M. da Fonseca, Instituto Superior Técnico, Lisboa/P
11:50
The characterisation and optimisation of biological hydrogen production by Escherichia coli HD701
C.R. Thomas,
M. Sulu
, University or Birmingham/UK; C.J. Hewitt, Loughborough University, Leicestershire/UK
12:15 Lunch
Room: Auditorium 1.16, building 8/9
Biocatalysis and Biotransformation
Chair: A. Schmid, Technical University of Dortmund/D
15:00
Process intensification of whole-cell biocatalysis with hydrophobic ionic liquids
D. Weuster-Botz, Technical University of Munich, Garching/D
15:25
Improvement of P450 whole-cell biocatalysis with E. coli by combining metabolic and bioprocess engineering
H. Schewe
, B. Kaup, J. Schrader, DECHEMA e.V., Frankfurt am Main/D
15:50
Bioelectrocatalysis with P450 - spectroelectrochemical characterisation of mediated electron transfer
S. Zengin,
D. Holtmann
, K.-M. Mangold, J. Schrader, DECHEMA e.V., Frankfurt am Main/D
16:15
Bioredox enzymes: fine chemicals applications beyond ketone reductions
S. De Wildeman, DSM, Geleen/NL
16:40 Time for room change
Room: Auditorium 1.2, building 8/9
Miniaturisation in Bioengineering and Nanobiotechnology
Chair: G.N.M. Ferreira, University of Algarve, Faro/P
09:50
Development of continuous culture microbioreactors
D. Schäpper
, K.V. Gernaey, A. Eliasson Lantz, Technical University of Denmark, Lyngby/DK; S. Stocks, Novozymes A/S, Bagsværd/DK; N. Szita, University College London/UK
10:15
Enzyme-catalyzed reactions at the microreactor scale
P. Žnidaršiè-Plazl,
A. Pohar
, I. Plazl, University of Ljubljana/SLO
10:40 Coffee Break
Chair: J. Büchs, RWTH Aachen/D
11:00
Printing nanosized molecular architectures with biomolecules at the diffraction limit: biosensor applications
M.T. Neves-Petersen
, E. Skovsen, A. Kold, S.B. Petersen, University of Aalborg/DK
11:25
Integrated optoelectronic detection of molecular recognition reactions for lab-on-a-chip application
D.M.F. Prazeres
, Instituto Superior Técnico, Lisbon/P; A.T. Pereira, Instituto Superior Técnico and INESC Microsistemas e Nanotecnologias, Lisbon/P; A.C. Pimentel, A. Gouvea, V. Chu, INESC Microsistemas e Nanotecnologias, Lisbon/P; J.P. Conde, Instituto Superior Técnico and INESC Microsistemas e Nanotecnologias, Lisbon/P
11:50
Colloidal gold nanoparticles for biosensing applications
R. Baltazar
, G.N.M. Ferreira, University of Algarve, Faro/P
12:15 Lunch
Room: Auditorium 1.2, building 8/9
Biothermodynamics
Chair: A. Jungbauer, University of Natural Resources and Applied Life Sciences, Vienna/A
15:00
Solubility of biological and industrial important organic compounds
F. Tumakaka
, G. Sadowski, J.B. Große Daldrup, G. Schembecker, Dortmund University of Technology/D
15:25
Parameters determining solubility of inclusion bodies and their refolding yield
A. Dürauer
, W. Sprinzl, A. Jungbauer, R. Hahn, Austrian Center of Biopharmaceutical Technology, Vienna/A
15.50
Interrelating protein precipitation and hydrophobic interaction chromatography
B.K. Nfor
, K. Wiedhaup, T. Ahamed, L. van der Wielen, G. van Dedem, M. Ottens, Technical University of Delft/NL; E. van de Sandt, DSM Anti-Infectives, Delft/NL; M. Eppink, N.V. Organon, Oss/NL
16:15
Temperature-induced conformational changes of pDNA and their influence on histidine-agarose retention – a circular dichroism study
F. Sousa
, University of Beira Interior, Covilhã/P; D.M.F. Prazeres, Instituto Superior Técnico, Lisboa/P; J.A. Queiroz, University of Beira Interior, Covilhã/P
16:40 Time for room change
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